If you can’t afford Camtasia, then you can consider this as a viable option. User-friendly screen recording tool with additional simulation, multimedia and single-sourcing features. Quality is very important in today’s eLearning videos and Ezvid allows you to benefit from today’s HD video technology.įree download available and all features offered in the free version. This screen recording tool allows you to produce computer narration for your video. Screen recording and video creation in the same platform. ISpring allows eLearning professionals to choose what sounds they wish to include in the video, such as system sounds or background music, as well as remove any background noise.Įzvid makes screen recording Ez to do! As the name suggests, Ezvid’s user-friendly interface is its main advantage, and that’s why it’s considered one of the best free Camtasia Studio alternatives.Įzvid brings two very important features in one program. Users can include microphone speech in the design of their videos with this feature. You can define what part of the screen you wish to record including individual windows. It is also a functional software for creating professional videos and eLearning presentations with a built-in video and audio editor. There is no premium version of Camstudio.įree Cam is one of the most professional Camtasia Studio alternatives. Video files are relatively smaller compared to competitive products, which enables faster uploading to the LMS as well as more efficient loading times when used by online learners. With Camstudio you can produce picture-in-picture webcam recordings along with screen recordings.Ĭamstudio allows you to record not only your pc screen, but also sound from any program or application you wish to include. One of its top advantages is that it will not burden your eLearning project with additional expenses. Although not even closely as impressive as Camtasia, it does get the job done effectively for simple projects. This is one of the best free Camtasia Studio alternatives. What makes FFsplit one of the best free Camtasia Studio alternatives is great features such as hotkeys, webcam and overlay, that give it quite the edge over more simplistic screen recording tools.įFsplit is more than a screen recording tool, it’s a supportive online community where everyone tries to improve the platform and aid other users as well. What’s more, you can also stream it live or upload it to your personal website or any other source. The first in our list of free Camtasia Studio alternatives comes with a great deal of features, an online community, and great capture and record functionalities.įFsplit allows you to capture and record whatever you have on your desktop. Here are the top 10 free Camtasia Studio alternatives that are bound to make the design of your eLearning course quite easier without burdening your eLearning budget at all. Screen recording tools also enable eLearning professionals to create video files in many different formats so that all users will be able to access them. Quite essential and time-saving, as this reduces their need to design videos or graphics from scratch by using or modifying the ones available on the Internet. Screen recording tools help eLearning professionals record and edit different parts of their computer screen and use them as they see fit. Contemporary online training programs are quite versatile and comprise a combination of features such as videos, pictures, graphics and text.
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Furthermore, none of these therapies showed simultaneous benefit for symptomatic relief, haemodynamic improvement, increased survival and end-organ protection. Although, the majority of patients admitted with PO rapidly improve as result of conventional intravenous (IV) therapies, treatment of PO remains largely opinion based as there is a general lack of good evidence to guide therapy. PO represents a medical emergency and treatment should be individually tailored to the urgency of the presentation and acute haemodynamic characteristics. However, recent studies have demonstrated that PO formation and resolution is critically regulated by active endothelial and alveolar signalling. The clinical picture of PO is dominated by signs of pulmonary congestion, and its pathogenesis has been attributed predominantly to an imbalance in Starling forces across the alveolar–capillary barrier. Pulmonary oedema (PO) is a common manifestation of acute heart failure (AHF) and is associated with a high-acuity presentation and with poor in-hospital outcomes. With three warehouse operations Yankee Clipper can meet and exceed the logistics needs of its' clients. Today, Yankee Clipper Distribution provides solutions in two of the largest US markets, that being the New York City and Los Angeles areas. We continue to acquire talent as we grow the Yankee Clipper family with quality people who understand the mission "Providing the complete third party logistics service to our customers".Īs for technology Yankee Clipper employs both automated and manual sortation systems, as well as Power House (QSSI) and W.I.S.E (Royal 4 Systems) warehouse management solutions (WMS). Kelly, Pavan's wife, brings a solid understanding of the inner workings of the 3PL world as well as a balance to Pavan's superior leadership and relationship building skills. And thus the Yankee Clipper tradition was born.Īs time went on the Yankee Clipper family has grown. As time went on Pavan realized he could provide warehousing, inventoryĬontrol and distribution solutions to other industries as well. He soon learned that he could bring 3PL solutions to the best of the apparel industry and serve as a quality conduit to their vital retail partners. All these superior specs mean their clippers run cooler and allow you to cut through pet. Their clipper blades are stronger, sharper, and run cooler, and the cord is 18 ft instead of 14 ft. Their superior clippers are twice as fast, half the weight, and offer an industry best warranty 5 years instead of 1. Along the way he came to realize his passion. Laube Clippers are simply the best clippers for Veterinarians and Professional Groomers. Two decades ago Pavan Makker came to America in search of his MBA. The Laube iVac Clippers is the best, handiest, multi-client and multi-purposed grooming tool and clipper. This next LOL Doll coloring sheet has a doll with a lot of attitude! She’s wearing an outfit that’s a little more pared back than the previous ones, so maybe you could use some milder colors for her. What are some other ways you can think of that would suit this look? This would further fit the style of this dress, but it is just one of the ways you could color her outfit. If we were to color this one in, we would use some bright neon colors done with mediums such as colored pens or markers. There are some cool triangular shapes on this dress, and they allow for all sorts of great color choices. This LOL Doll coloring sheet features a doll in an outfit that has a bit of a vintage style. What bright colors will you use for this rocking LOL Doll prountable? Get ready to rock and roll with this awesome LOL Doll coloring page! This little rockstar is looking really cool, and she needs some great colors to finish off her look.įor this rocker, I would use some bright pinks and purples to really finish off her punk, rockstar style that she has going on. There are a lot of great small details in her hair, so I think using some colored pens and pencils would really help to add some great color details.įor this fun doll, I think the more color you can add the better! I think we can all agree that the doll in this LOL Doll coloring printable has some big hair and an even bigger personality! She must have a strong neck to carry around that majestic hairdo all day. We can’t wait to see what colors you use for this LOL Doll. Because of this, you could use your favorite colors on it and I know it will look so great! We’re ready for some fashion fun in this stylish LOL Doll coloring sheet! This doll definitely looks ready for the runway.įor this picture, I think any kind of color style would suit it perfectly. I would use some colored pens for some of the details in this image to really make her a fashionable star! This first image in this set of free LOL Doll coloring pages for kids has a fancy diva who looks like she’s singing her heart out!įor this funky singer, I would definitely think that bright, bold colors are the way to go. 30 Brand New LOL Doll Coloring Pages – Free to Print and Color We always love to see your colorful and artistic creations, and we can’t wait to see how you color in these LOL Doll printables. Once you’ve colored in your favorite LOL Doll coloring sheets, please share them to our Facebook page for us to see! You could even incorporate different mediums like paints and pens along with other crafts to really put your own spin on these cute dolls. This awesome coloring page collection features dolls in many different styles and outfits for you to use your coloring talents on! These free LOL Doll coloring pages for kids are the perfect way to have hours of coloring fun with your favorite fashionable friends. LOL Dolls are definitely one of those that have stayed super popular with new fans joining every day! New toy crazes seem to sweep the world every week! Popular toy brands come and go, but some manage to stick around for a long time with millions of fans. A decent password generator can generate long passwords that include lower and upper case letters, numbers, and special characters (such as &, !, %, and #). The most secure way to do so is to utilize a good password generator to provide you with more full-proof passwords. For that reason, some laptops and mobile devices include alternative iris and fingerprint reader login methods for users to utilize.Īlso, you can only password protect your RAR archives. Yet, many users will often come up with weak passwords for accounts and RAR files. The fact is that weak passwords aren’t entirely secure. Why do People Need RAR Password Generators? Top 8 Best Password Generators for RAR Files.Why do People Need RAR Password Generators?.The list below includes some of the best RAR password generators. There are various password generator tools you can utilize in browsers and download that automatically generate random character passwords for users. So, you’ll need to manually come up with suitable passwords for your RAR files.Īlternatively, you could find a good password generator for encrypted RAR files. However, WinRAR doesn’t include a password generator tool. You can also add passwords to RAR files with the WinRAR compression utility. WinRAR is the default software for creating RAR archives and extracting them. RAR archives have advanced AES 256-bit encryption, which is among the best encryption algorithms. Users can add passwords to RAR files to protect their contents. That’s not surprising given the fact RAR is a more efficient archive format than ZIP with a superior compression method.Īside from file compression, RAR archives can also come in handy for data encryption. Although ZIP is more widely utilized, some users prefer to compress file groups to smaller sizes with RAR archives. RAR is an archive file format some users compress files with. On the original Facebook video, he wrote: "I was just high on life everything was going my way and I've seen people do it before only I remembered after I jump(ed) that was in movies. "But after the fact, after realizing it was a bad idea, everything else I did was in pure survival mode." "It was crazy to do what I did," he said. They were telling me to 'get on the ground, get on the ground.' So I got on the ground, listened to them, and they put me handcuffs."Īfter being treated in hospital, he was cited for criminal mischief and criminal trespassing. "I was walking and heard officers come behind me with their guns and told me to put my hands up, but I couldn't since I hurt my shoulders from the fall," He said. But after spending hours looking for him, they were not too happy to see him. So he borrowed a boat he found, and crossed back to the mainland, where he finally ran into the police. Wandering around barefoot, he stumbled across an ATV after riding that around lost for an hour, he finally realized he was actually stranded on an island. I had to walk, where I was at, I couldn't even see the bridge anymore," Jennings told ABC13. "It was pretty crazy me getting back to shore. Lightning Strikes Texas Teen's Golf Ball Mid-FlightĪfter struggling to tread water for three hours, the current finally weakened enough for him to make to to shore. I really and truly thought it was the end of my time. "I started going under and almost drowned a few times. "I turned onto my back and would push with my right hand and my legs whenever I went under. "An hour and a half in, I was so tired of swimming. I tried to swim to the shore, but the current was too strong." "Once I hit the water, my mouth busted open and I hurt my left arm. "As soon as my fingertips came off that side, I was like, 'Oh my god, this was the stupidest idea.'" I looked down (at the water), and it didn't seem too far," he told the site. He told his pal Khory Vaughan he was going to jump into the river, swim to shore and get picked up at the next exit. There, they located a male subject lying on the ground and repeatedly clutching his head. The Lafayette resident told NY Daily News he'd been sitting in his car on Atchafalaya Basin Bridge for two hours after a ten-vehicle collision brought traffic to a standstill. CBS Austin confirmed with Austin-Travis County EMS that on Monday, November 23rd, medics responded to an 'unknown' call at Plaza on the Lake at 2:34p.m, following the jump. Stomach-Churning Moment Swing Above 6,300ft-High Canyon SNAPS Cake cutting fees – Sometimes venues will charge this if you bring in a cake from an outside vendor.Card box – So that your guests will know where to put their cards and gifts.alcohol (beers or champagne) for the ride to the reception.limo/trolley for bridal party and parents.for guests to/from ceremony, reception, hotel, etc.Attire (Rehearsal dinner) – Dress, shoes, jewelry, accessories.Accommodation – We all know about the wedding night hotel, but where will you be sleeping the night BEFORE your wedding? ($free – $400).
And you’ll need to use flux core wire to get good penetration. Your Lincoln Easy MIG 140 can even weld up to 5/16th of an inch thick mild steel.īut when you’re welding 1/4 inch to 5/16ths mild steel you’ll need to take multiple welding passes. Your Lincoln MIG 140 welder will weld mild steel sizes from 24 gauge through to 3/16th of an inch in a single pass. Weld Pak 140 Circuit Breaker On Back Lincoln MIG 140 Metals And Thickness Welded Lincoln Electric Easy MIG 140 Flux-Core/MIG Welder Here in this under 3 minute YouTube video, it’s under its Easy MIG 140 guise Time for you to take a look at an overview of this Weld Pak 140HD. And the thickness of the metal you can weld.Īnd you can feast on those facts a little later on in the post. They tell you how long you can use your welder for. You look at the welder’s duty cycle, voltage output and thickness of metal you can weld. How do you judge a light to medium welding job? Your Lincoln Electric 140 HD Weld Pak is light enough for you to take to a repair out in the field or on your farm. Like those straight forward but important repairs around your home and yard. When you’ve light bordering on medium welding jobs. One that you can carry with you to those jobs where you don’t need a stronger welder. Or if you’re a master welder looking for a solid MIG welder. You can grab the Lincoln 140 Weld Pak if you’re just starting out on your MIG welding journey. Review And Overview Of The Lincoln Weld Pak 140 HD I have an article you might want to read first. Not sure how to go about picking the right MIG welder? The Lincoln 140HD Weld Pak or 140 Pro MIG welder or the 140 MIG Pak and the 140 Easy MIG welder.Īnd I’ll use the names through out this post.Ĭause what they call it really doesn’t matter. The review you read here is valid for them all. Lincoln Electric sells direct on its website the MIG Pak 140. Lincoln Weld Pak 140 HD’s are typically sold by Home Depot. The different names mean each partner can sell the same welder under their own brand.Īnd a name that makes it sound like it’s a specific welder only they sell. Lincoln Electric sells this welder through a few distribution partners. Why do all these Lincoln 140 spec’s look the same?Īnd why does Lincoln have so many MIGs with the same specs? So how do there specs compare? Weld Pak 140HD You’ll find your Lincoln Weld Pak 140 HD sold and called many names. Who Designs And Manufactures The Lincoln Electric Weld Pak 140 HD?.Is Your Lincoln Electric Weld Pak 140 HD Portable?.YouTube Lincoln HD Video Moment 2, Unboxing The Weld Pak 140HD.What Comes In The Box With Your Weld Pak 140?.What Do Users Of The Lincoln Electric 140 HD Weld Pak Think?.Welding Aluminum With Lincoln 140 MIG Pak.Lincoln MIG Pak 140 Changing Welding Polarity.What Shielding Gas Can The Lincoln Electric 140 Welder Use?.The Wire Feed Drive System On The 140 Weld Pak.Lincoln MIG 140 Metals And Thickness Welded.The Lincoln 140HD Weld Pak's Protection From Over Heating.Lincoln 140HD MIG Welder Output Controls.Review And Overview Of The Lincoln Weld Pak 140 HD. So if you are looking for that unique addition to your man cave, bicycle collection, or beer memorabilia. Other than that this bike is perfect! The tires have the nubs still on them and everything. Lastly, the sticker on the chain guard has one small spot that it got scuffed(see picture) size of a dime or smaller. The back fender also has a very small scuff from moving. The paint is phenomenal, but it has two- three very small chips the size of a pencil tip near the seat post. The bike is new old stock in the fact it has never been ridden(hung in a bar most of it's life) but it does have a few very minor flaws. The bike is rare in the fact not many of these were made in the early years and those that were had been only given away to certain employees, charity events, or other promotional uses. This bike is a beautiful yellow metallic color with great lines and style. And was the second year these New Belgium Fat. Thanks,įat Tire New Belgium Brewing Edition Bicycle The bike is a 2000 model made by the Electra Bicycle Company. We are willing to respond to your inquiry. Feedback If you have any concerns about the item to us. New state must be Shipping and handling are non-refundable. Including all packaging materials, in the original box unopened. Return Policy We carefully inspect items before shipment is. Payment We officially use PayPal to customers. We can send a combined shipping invoice for you. And after checked a multiple purchase, Please contact us before the payment. With tracking number) Combined shipping discounts We can combine shipping. With tracking number) Express delivery takes 4-10 business days after shipment. more Economy Shipping will take 20-30 business days after shipping(without tracking number) Standard shipping will take 20-30 business days after shipment. Last Updated on: Jwith Electra Rat Rod 26” wheels rare beach cruiser bike.Electra all accessory is compatible with other bikes* Shipping The post office via airmail within 2 business days for your order to ship. 26” front wheel and 24x3.0 rear wheel with Fatti O tire. This is the a Gloss Black Aliminum Frame Rat Rod known as a Deluxe model amongst collectors. Super Clean Electra Aluminum Rat Rod 3i cruiser. Super Clean Electra Rat Rod Deluxe 3 Speed Beach Cruiser - $425 (Sun City).This is the last rat rod version Electra made. And all original except for the handlebars. This is the final generation of the Electra Rat Rod. Men’s electra rat rod 3speed - $400 (Westminster).Electra paid tribute to legendary hot rod designer, Ed Roth with this Rat Rod model and a lime green Rat Fink. 20 in Electra “pedal forward” bicycle is a special blacked out flames paint job Rat Rod model with embroidered leather flame hand grips. This bicycle is essentially unused/brand new. Electra Rat Rod 20” bicycle - $125 (Washington Twp / Sewell). There is some normal to be expected wear and tear which I tried to capture in the pho. I am selling my 26" ELECTRA Rat Rod bike at a super low price, need to sell fast we will be moving soon and don't want to take it along-no space. Hi there! Thanks for stopping by to check out my ad. ☆☆☆MUST SELL NOW!! 26" ELECTRA Rat Rod Cruiser Bike☆☆☆ - $139 (Turlock).Recently replaced original electra tires with new tires and tubes. Has shimano nexus internally geared 3 speed. It's in great shape and operatesperfectly. I'm selling a early model electra rat rod bicycle from the 1970-1980's. Bike has been used, signals of normal wear as you see at the photos, super comfortable and rare beach cruiser, you won’t be disappointed, 3 speeds shimano nexus drivetrain, and 26” e the original photos of the ac. Post will be delete immediately after sold, so it’s available. Electra Rat Rod 26” wheels rare beach cruiser bike. Based on compelling evidence from both cell-based FGF2 secretion experiments and biochemical in vitro studies, unconventional secretion of FGF2 was shown to follow a type I mechanism that is based on direct protein translocation across the plasma membrane ( La Venuta et al., 2015 Zhang and Schekman, 2013 Malhotra, 2013 Nickel, 2005 Schäfer et al., 2004). Two of these pathways concern soluble proteins derived from the cytoplasm that are transported into the extracellular space by either direct protein translocation across the plasma membrane (type I unconventional secretion) or vesicular mechanisms involving endosomal compartments (type III unconventional secretion) ( Rabouille et al., 2012 Zhang and Schekman, 2013 Piccioli and Rubartelli, 2013). The term unconventional secretion has been used for four different pathways of protein transport towards the plasma membrane and the extracellular space ( Rabouille et al., 2012). This process is believed to represent a frequent cause of tumor cell resistance against conventional anti-cancer therapies.Īs opposed to other FGF family members, FGF2 lacks a signal peptide and is transported into the extracellular space by an ER/Golgi-independent mechanism ( La Venuta et al., 2015 Nickel, 2011 Nickel and Rabouille, 2009, 2008). In addition, FGF2 acts as a survival factor that inhibits tumor cell apoptosis by an autocrine secretion-signaling loop ( Noh et al., 2014 Pardo et al., 2006). This is particularly evident in the context of cancer with FGF2 being a major mediator of tumor-induced angiogenesis ( Presta et al., 2005). FGF2 is the prototype member of this family that, beyond the functions of FGFs in normal cell growth and differentiation, plays critical roles under pathophysiological conditions ( Akl et al., 2016). They are of critical importance for physiological processes such as embryonic development, tissue regeneration, wound repair and hematopoiesis ( Bikfalvi et al., 1997). Our combined findings establish a novel type of self-sustained protein translocation across membranes revealing the molecular basis of the unconventional secretory pathway of FGF2.įibroblast Growth Factors (FGFs) form a family of more than 20 potent mitogens that stimulate the growth of a wide range of cells including fibroblasts and endothelial cells ( Bikfalvi et al., 1997). Based on atomistic molecular dynamics simulations, we propose a mechanism that drives PI(4,5)P 2 dependent oligomerization of FGF2. Vectorial translocation of FGF2 across the membrane is governed by sequential and mutually exclusive interactions with PI(4,5)P 2 and heparan sulfates on opposing sides of the membrane. The latter serve as dynamic translocation intermediates of FGF2 with a subunit number in the range of 8-12 FGF2 molecules. FGF2 membrane translocation is thermodynamically driven by PI(4,5)P 2-induced membrane insertion of FGF2 oligomers. Here, we define the minimal molecular machinery required for FGF2 membrane translocation in a fully reconstituted inside-out vesicle system. This process is mediated by direct translocation across the plasma membrane. Cancer Res 1997 57: 4063–4069.FGF2 is secreted from cells by an unconventional secretory pathway. AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal. Tewari M, Yu M, Ross B, Dean C, Giordano A, Rubin R. FIF, a nuclear putatively antiapoptotic factor, interacts specifically with FGF-2. Van den Berghe L, Laurell H, Huez I, Zanibellato C, Prats H, Bugler B. The high molecular weight isoforms of basic fibroblast growth factor (FGF-2): an insight into an intracrine mechanism. Both normal and tumor cells produce basic fibroblast growth factor. Moscatelli D, Presta M, Joseph-Silverstein J, Rifkin DB. Expression of basic fibroblast growth factor (bFGF) and FGF-receptors in human leukemic cells. Blood 1999 94: 3334–3339.Īllouche M, Bayard F, Clamens S, Fillola G, Sie P, Amalric F. A high pretreatment serum basic fibroblast growth factor concentration is an independent predictor of poor prognosis in non-Hodgkin's lymphoma. Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood 1999 94: 1077–1085.Īguayo A, Kantarjian H, Manshouri T, Gidel C, Estey E, Thomas D et al. Basic fibroblast growth factor is expressed by CD19/CD11c-positive cells in hairy cell leukemia. Gruber G, Schwarzmeier JD, Shehata M, Hilgarth M, Berger R. |
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